Epstein Julie Dr, Moore Park, NSW
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Serious Doubts Raised About Study Conclusions : Serious doubts are now being raised in mainstream medicine about the conclusions reached by the WHI Study team, and many are now questioning how such a flawed study can have received the broad acceptance that it did. Le me give you some background.. In 1991 an international study involving more than 15, 000 women was launched to, among other things, study the effects of hormone replacement therapy on the health of postmenopausal women. By 2002, that part of the study had been terminated and researchers reported that there was a "significant increased risk" of heart attack, stroke and breast cancer in the HRT group. That finding made world wide headlines and as a result, millions of women discontinued their HRT treastment. The problem was, the study was seriously flawed. First, the HRT being used was the synthetic Provera, a molecule that mimics just a small part of a woman's natural progesterone while haven a chain tacked onto the side so it's makers could patent it. It's call a 'progestin'. It was the wrong hormone. Second, the participants were all POST menopausal. Other studies conducted on menopausal women show a different result, and these may well be a truer reflection of the effectiveness of HRT. The short summary is a simple one.. the WHI study focused on the wrong hormone in the wrong women using the wrong delivery system, and it misrepresented risks by a trick of statistics. In a sense, it was actually a good study.. Provera when commenced post menopausally, does cause a very slight increase in risk. The conclusion ought to have been "don't take Provera". Really, it's not that hard to figure that out.
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